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Terahertz Applications Group

Department of Chemical Engineering and Biotechnology

Studying at Cambridge



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20 Years, Chemical Engineering Strikes Back

Mar 27, 2013
First dedicated chemical engineering conference was carried out by IChemE at Imperial College London

3rd Terahertz Spectroscopy Meeting

Oct 31, 2013
All current members of our group attended the 3rd Terahertz Spectroscopy Meeting organised by the Molecular Spectroscopy Group and the East Anglia Region of the RSC.

Californication for the TAG Postdocs

Dec 13, 2017
Daniel and Mike headed to the American Association of Pharmaceutical Scientists 2017 meeting in San Diego, California, where they discussed their current work.

Axel Delivers Invited Lecture at IRDG 213

Apr 21, 2016
Axel presented a summary of terahertz applications to the Infrared and Raman Discussion Group meeting held at the Renishaw Headquarters in Gloucestershire

TAG First to Publish CC-BY Preprint on ChemRxiv

Aug 22, 2017
New research from the TAG group has appeared on the ChemRxiv preprint server, representing the very first submission to make use of the fully-open source CC-BY license.

End to a Great Conference Season

Nov 02, 2016
September was a busy month for the members of the TAG group! The group spent a majority of the month travelling around the world to present their work and catch up collaborators. The month was capped off by the annual IRMMW-THz meeting, which was held in Copenhagen this year.

Farewell to Johanna

Nov 02, 2016
Johanna Sauerwein, an undergraduate student from Friedrich Schiller University Jena in Germany, has completed a highly productive three-month visit to the TAG group today. She was a valuable addition to the lab, and was a critical component of the research performed during her time. She effectively immersed herself in all areas of research, both on the imaging and spectroscopic sides. She will be sorely missed!

The Terahertz Application Group Welcomes New Members

Apr 18, 2016
The Terahertz Applications Group has undergone a dynamic shift over the past few months, as (now) former members have moved on to new positions and a new team has taken over.

TAG Welcomes Two New PhD Students

Oct 26, 2017
The TAG welcomes Qi Li and Mohammed Al-Sharabi, who both started working on their PhD degrees this fall.

Members of the Terahertz Applications Group Present Work in Glasgow, Scotland

Apr 18, 2016
Daniel Markl and Michael Ruggiero presented work at the 10th Annual World Meeting on Pharmaceutics, Biopharmaceutics, and Pharmaceutical Technology in Glasgow, Scotland. Daniel presented his poster titled 'Mechanistic Understanding of Disintegration in Immediate Release Tablets', and Michael delivered a presentation titled 'Stability Prediction of Amorphous Drug Molecules'.

Terahertz Applications Group at PSSRC 2014 Ljubljana

Sep 25, 2014
We Presented at the 8th annual symposium of the Pharmaceutical Solid State Research Cluster at the University of Ljubljana in Slovenia.

Spectroscopy Research Featured on Cover of Angewandte Chemie

Jun 02, 2016
Recent work performed in collaboration with researchers at Syracuse University on connecting the terahertz vibrational motions of polyproline helices to their elasticity is featured on the cover of Angewandte Chemie.

A new method for prediction of amorphous drug stability

Apr 01, 2014
A new method for measuring of molecular mobility in glassy materials has been developed using terahertz spectroscopy. The absorption level of amorphous drugs at terahertz frequencies below Tg correlates with the stability of the drug as an amorphous solid. The molecular mobility responsible for the glass crystallisation significantly decreases at around a universal value of 0.67 Tg. This explains why the commonly used rules of thumb for glasses to remain stable below 0.8 Tg or Tg – 20 K do not work reliably.


Site News

Presentation at Dielectic Spectroscopy Conference BDS 2014

Oct 01, 2014

CDT in Sensor Technologies and Application funded

Mar 31, 2014
One new centre providing postgraduate training approved by the Engineering and Physical Sciences Research Council (EPSRC): CDT in Sensor Technologies and Applications

CETIIB undergraduate research project successfully finished

Jun 08, 2013
08/06/2013: Miriam Franklin and Michael Sargent have successfully finished their CETIIB undergraduate research project on "Terahertz spectroscopy for polymer characterisation and investigation of amorphous pharmaceuticals". Well done!

Conference presentations at 2014 APSGB UKPharmSci meeting

Sep 10, 2014
We presented two posters and a talk at this year's annual meeting of the Academy of Pharmaceutical Sciences at the University of Hertfordshire.

Congratulations to Juraj for passing his viva!

May 23, 2014
Yesterday Juraj passed his viva for his PhD thesis on 'Terahertz spectroscopy of glasses and supercooled liquids'

Day meeting on THz spectroscopy in Cambridge 18 March 2016

Feb 09, 2016
Together with Teranet, an EPSRC-funded network of UK Universities and companies active in terahertz science and technology, the Molecular Spectroscopy Group and East Anglia Region of the Analytical Division of the RSC will jointly host the 4th terahertz spectroscopy meeting in Cambridge. Following three successful meetings in 2009, 2011 and 2013 with the RSC, this year's meeting is the first one involving Teranet and to mark the occasion we will return to Gonville & Caius College in Cambridge. The meeting will focus on recent advances in terahertz spectroscopy.

Debye and THz absorption analysis of binary liquid mixtures

Feb 05, 2015
Probing hydrogen bonding in liquids in the THz region with Debye and absorption analysis

Editor's choice paper

Oct 05, 2013
A paper published by the Terahertz Applications Group earlier in the year was selected by the editors of the Journal of Pharmaceutical Sciences as their pick of the most original and most significant scientific findings published in the preceding three issues (July 2013 - September 2013).

Farewell to Nick Tan

May 21, 2015
Nick has just successfully defended his PhD thesis on "Terahertz spectroscopy of organic systems with bulk structural order and disorder"

Farewell to Tim Korter

Jun 01, 2015
Professor Tim Korter has just completed his visit to our group for three months as part of his sabbatical from March to May.

Group Members Attend the Rank Prize Funds Symposium on Terahertz Technologies

Jun 21, 2016
Axel and Mike, along with group alumnus Hungyen, delivered a series of lectures at the prestigious Rank Prize Funds Symposium on Terahertz Emitters and Emerging Applications in Grasmere, UK. They were joined by leaders throughout the entire Terahertz field for a week of very productive seminars and meetings.

In-line Measurement of Film Coating Processes

Nov 11, 2014
Hungyen recently delivered an invited talk titled 'In-line Measurement of Film Coating Processes' as part of the'Expert of Solids' certification Seminar on November 18 to 20 hosted by Bosch Packaging Technology/Huettlin GmbH in Germany.

In-line Measurement of Film Coating Processes

Jun 24, 2015
Bosch Packaging Technology/Huettlin GmbH in Germany recently hosted the 'Expert of Solids' certification Seminar where Hungyen delivered an invited talk titled 'In-line Measurement of Film Coating Processes'

Italy tour on terahertz spectroscopy of amorphous systems

Apr 10, 2015
Juraj recently visited the University of Pisa and delivered a seminar talk, followed by an oral and a poster presentation at the XIV International Workshop on Complex Systems in Fai della Paganella.

Keynote presentation at EuPAT7

May 19, 2015
On 19 May Axel gave a presentation at the EuPAT meeting in Graz, Austria on "Terahertz pulsed imaging and optical coherence tomography - novel sensing approaches in secondary pharmaceutical processing and development".

Mike Hits Up Japan

Dec 13, 2017
Mike Ruggiero presented his latest research as an invited speaker at the MTSA2017 terahertz meeting in Okayama, Japan.

PRACE and CECAM Molecular Simulation Workshop in Dublin

Jun 21, 2016
Mike attended and presented work at a PRACE and CECAM sponsored workshop on high performance computing and molecular simulation in Dublin, Ireland in May. The workshop highlighted recent technological advances in computing, and the resulting new horizons for modelling molecular systems.

New Commercial Teraview Spectrometer Delivered

Apr 21, 2016
A brand new commercial terahertz spectrometer was delivered today. The instrument was built by local manufacturer Teraview Limited.

New MPhil student joins the group

Mar 13, 2015
Welcome to Jade Wong, who joined our group on 13 March to work with us on analysing solvent transport in rock cores using terahertz pulsed imaging.

New paper: Evidence for a universal change in hydrogen bonding structure below the glass transition temperature

May 21, 2014
In our latest paper, just published in the Journal of Physical Chemistry Letters, we present data that indicates that the Johari-Goldstein secondary relaxation (which is inter-molecular in nature) is still of significant strength at terahertz frequencies below the glass transition temperature. Intriguingly we found that it disappears at the same relative temperature in all hydrogen bonding samples we studied (0.65 T/Tg).

New Paper in ACS Nano

Feb 14, 2014
Low-Bias THz Amplitude Modulator Based on Split-Ring Resonators and Graphene

New paper: Crystallisation and phase changes from amorphous paracetamol

Mar 21, 2014
We used terahertz spectroscopy to investigate the crystallisation and phase changes in paracetamol from the amorphous solid to the liquid phase

New paper published in Materials Horizons

Feb 10, 2014
Work on restricted intramolecular rotations of tetraphenylethylene was published in Materials Horizons, a new journal launched by the RSC earlier this year.

New Paper: Terahertz Sensor for Measuring the Film Thickness of Automotive Paint

Aug 26, 2014
Together with Yaochun Shen at the University of Liverpool and our industrial collaboration partners we have developed a terahertz sensor for non-contact thickness and quality measurement of automobile paints.

New Research Into Crystalline Anharmonicity Published in the Journal of Physical Chemistry B

Nov 02, 2016
The work showcases the ability of terahertz spectroscopy to probe temperature dependant changes in the low-frequency vibrational modes, and ultimately relates them to intermolecular anharmonicity.

Open postdoc position

May 21, 2014
We are looking for a postdoc to work with us on the application of THz-TDS for the quantitative analysis of solvation shells around macromolecules.

PhD Studentship available in our group

Apr 02, 2014
A studentship is available in our group to investigate the dynamics of hydrogen-bonded amorphous drug molecules at terahertz frequencies

Review Article Featured on Cover of European Pharmaceutical Review

Nov 02, 2016
A review of the pharmaceutical applications of Terahertz radiation written by members of the TAG group was recently featured on the cover of the European Pharmaceutical Review. Well done to everyone!

Simvastatin phase transitions probed by terahertz spectroscopy

Feb 05, 2015
Simvastatin phase transitions probed by terahertz spectroscopy

Summer Fun! TAG Swells in the Summer of 2017

Aug 22, 2017
We've welcomed four new group members this summer, three undergraduate research students and one masters student, who have been busy at work unravelling the mysteries of terahertz science.

TAG explores high-intensity terahertz radiation from Free Electron Laser

Feb 17, 2015
The free electron laser FLARE (Nijmegen, the Netherlands) offers access to high-intensity terahertz radiation.

TAG Goes to Lille

Jul 07, 2013
Group visit to the annual meeting of the Pharmaceutical Solid State Research Cluster

TAG Hosts Meeting on In-line Sensing of Pharmaceutical Coating Processes

Apr 21, 2015
In-line Sensing of Pharmaceutical Coating Processes

TAG joins Faraday Discussion 167

Sep 18, 2013
TAG participated in RSC Faraday Discussion 167: Mesostructure and dynamics in liquids and solutions

TAG participated in 9th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology and APS Amorphous by Design 2014

May 23, 2014

TAG Research is Most Downloaded in 90 Days

Aug 22, 2017
Research from the TAG group was listed as one of the 'Most Downloaded' articles in the International Journal of Pharmaceutics.

New TSB grant

Jan 01, 2013
The TSB awarded a grant to the Terahertz Application Group to develop a terahertz sensor for automobiles paints measurement

TAG Welcomes a New Visitor

Nov 21, 2016
Xudong Liu is visiting the TAG group for the next 6 months! Welcome to Cambridge and the TAG group!